Tag Archives 杭州水磨

“Emmanuella” pays courtesy call on Minister Norton

first_imgThe cast of Mark Angel Comedy on Tuesday paid a courtesy call on Social Cohesion Minister Dr George Norton.Emmanuella Samuel and Aunty Success posed with Dr George NortonMark Angel, a Nigerian video producer, is best known for the Mark Angel Comedy series, which usually features child comedians— including his niece, nine-year-old Emmanuella Samuel and his sister, Aunty Success. In just a short period of time, the two girls have managed to create a massive stir on social media.The Mark Angel Comedy cast is currently in Guyana as part of a tour of the Caribbean. Minister Norton welcomed the team to the Land of Many Waters.Dr Norton is anticipating that Emmanuella and Aunty Success’ presence will inspire young comedians to start exploring their talents from an early age.Angel and his team are here to perform at the National Cultural Centre on Wednesday, August 7, 2019. The show, titled “Emmanuella for Emancipation”, will also include Kingsley, Amanda, Denilson, Uzoma and little Success. The show will be hosted by Guyana’s own Lyndon “Jumbie” Jones.Tickets for the event are $2500 for adults, $1500 for kids and $4000 for stage front.last_img read more

Kurtenbach: It’s a tricky, murky, and expensive (oh so expensive) path ahead for the Warriors

first_imgClick here if you’re unable to view the photo gallery on your mobile device. Related Articles The season is over, the Raptors are champions, and the Golden State Warriors have no choice but to head into the great unknown.After their performance this postseason, they can trudge forward with their heads held high.But that doesn’t make this summer any less daunting.center_img Warriors resemble team of old, Kevon Looney isn’t ready, and other thoughts from loss to Trail …last_img

Evolution As Catch-All Explanation

first_imgIn the scientific institutions and the media, Evolution is the default explanation for everything in nature (and as Small opined, even for human manufacturing and economics).  Most of the time Evolution doesn’t require justification or evidence.  It is applied in broad, sweeping generalities from the authorities.  The explanations are pronounced dogmatically as if to be accepted on faith by the common people.  In a sense, then, Evolution (with a capital E) plays the same role as gods and goddesses in ancient cultures.Silly, silly, silly.  These people only get away with saying such things because we are not laughing loud enough.  Look at them.  They worship cartoony idols (King Charles, Popeye, Yoda and Tinker Bell) that have magical powers.  They say things that not only make no sense, they plagiarize design words and contradict their own core beliefs.  They justify humans’ worst character flaws as artifacts of an animal past.  Get out on the yellow brick road and sing We’re off the shame the Wizard, the blunderful Wizard of Flaws (see lyrics in the 09/05/2008 commentary) as you accomplish your mission to expose charlatanry and bring science back to the real world.(Visited 36 times, 1 visits today)FacebookTwitterPinterestSave分享0 If you were taught a precise definition of neo-Darwinism in school, it doesn’t seem to matter to many evolutionists in the media.  In practice, the word “Evolution” seems to act as a catch-all category for explaining anything and everything – whether or not random mutation and natural selection were involved.  Some purpose and design can even be tossed into the mix as long as Evolution is the hero of the story.  Here are some recent examples of how Evolution is employed to explain whatever:Evolution the tool user:  “Evolution has a ‘toolkit’ and when it needs to do a particular job, such as see light, it uses the same toolkit again and again.”  These are the words of Margaret McFall-Ngai [U of Wisconsin-Madison] in Science Daily, explaining why squid can sense light through their light-emitting organs.  The article explained that “molecular machinery” is involved – tangible evidence not of design, but that Evolution has been at work with its toolkit.Guppy race:  Evolution is slow and gradual – except when it is fast and furious.  “What’s the secret to surviving during times of environmental change?” asked Science Daily.  “Evolve…quickly.”  (This sounds like a version of the bumper sticker, “Evolve or perish.”)  Guppies in Trinidad have apparently altered their reproductive habits in just eight years when transplanted to different streams – one with more predators, one with fewer.  How this constitutes evolution when the reproductive apparatus was the same before and after was not explained, but “fitness differences” were defined in terms of survival rate (see 10/30/2002, “Fitness for Dummies”).  Surprisingly, after 150 years of Darwinism, “This is one of only a few studies to look at adaptation and survival in a wild population,” the article said.Spanish hominid:  Evolution got the credit for a fossil monkey with “modern New Scientist) – something that might make Europeans feel superior once again as being in the forefront of human evolution.Mosquitos vs. turtles:  Who will win the evolutionary arms race in the Galapagos?  The mosquitos or the giant tortoises?  Science Daily seems alarmed about the danger to the long-time residents that are so popular with tourists: “Mosquito Evolution Spells Trouble For Galapagos Wildlife,” the article announced.  It said that an “ancient” mosquito population came to the islands 200,000 years ago and has recently developed a taste for tortoise blood.  Park officials are very concerned that diseases that could be introduced by tourists could spread to the island inhabitants, so they are taking precautions by spraying the interiors of planes arriving on the islands.  “It is absolutely vital that these control measures are maintained and carried out rigorously, otherwise the consequences could be very serious indeed,” a scientist said.  He did not explain why there should be a cause for concern, since all of the inhabitants of the islands supposedly evolved according to a well-known evolutionary dogma: the founder principle (see 05/08/2002 and 02/10/2009, bullet 4).  Are they ranking the organisms according to some arbitrary rule?  Are they claiming that human beings have some special stewardship responsibility over the animal kingdom?Saved by the junk:  Functional “junk DNA” has been an argument against evolution, but they have found a way to turn it into an argument for evolution.  PhysOrg printed a story that now claims junk DNA is vital to an animal’s survival – and therefore its evolution – because it allows an organism to adapt quickly.  Tandem repeats (once a category of junk DNA) have been found to influence the activity of neighboring genes.  This means they “may allow organisms to tune the activity of genes to match changing environments – a vital principle for survival in the endless evolutionary race.”  Researchers explained, “If this was the real world, only cells with the repeats would be able to swiftly adapt to changes, thereby beating their repeat-less counterparts in the game of evolution.  Their junk DNA saved their lives.”  They did not say who is playing the game or who wrote the game in the first place.Animorals:  Animals can tell right from wrong, claimed The Telegraph.  “Until recently, humans were thought to be the only species to experience complex emotions and have a sense of morality,” the article by Richard Gray said.  “But Prof Marc Bekoff, an ecologist at University of Colorado, Boulder, believes that morals are ‘hard-wired’ into the brains of all mammals and provide the ‘social glue’ that allow often aggressive and competitive animals to live together in groups.”  Gray did not explain what the moral standard was by which to judge moral behavior, nor why social glue is a good thing.  Some aggressive and competitive animals are loners.  If morality is hard-wired, is it really morality?  Who is the judge?Say what?  One article on Science Daily claim that a genetic change to the language-related FOXP2 gene in mice to make them mimic the human form of the gene speaks “volumes about our evolutionary past” (Note: the mice do not talk; they just squeak a little differently.)  Presumably, “Those differences offer a window into the evolution of speech and language capacity in the human brain.”  The scientists involved admitted that “Currently, one can only speculate about the role these effects may have played during human evolution.”  But then, another Science Daily four days earlier had announced, “More Genetic Differences Between Mice And Humans Than Previously Thought.”  It further claimed that some of the newly-analyzed mouse genes are “evolving at an unusually rapid pace, probably as a result of an evolutionary ‘arms race’ among mice and their reproductive cells.”Small talk on cars:  Evolution even applies to car companies.  That’s the point Meredith Small tried to make on Live Science.  Her article, “How Evolution Could Sink (or Save) GM,” contained the following statement, reminiscent of Rockefeller-era social Darwinism: “It would seem that the country should act as a collative [sic; collective?] and care about this,” (i.e., the bankruptcy of General Motors).  “But the reality is that capitalism is like evolution by natural selection, and natural selection can be a harsh reality.”  Taking the edge off, she launched into a discussion about group selection as a possible offset to the ruthlessness of natural selection.  But group selection, she said, doesn’t seem to make a lot of sense.  Why should we care about the job losses of people we don’t even know?  She quoted Bobbi Lowe (U of Michigan) who believes “humans are not well designed to operate” by caring for distant members of our species.  We only care about close kin, because that was “critical in our ancestral past when humans lived in small groups,” she explained.  “We also don’t plan well for the future because our hominid history was marked by uncontrollable, unpredictable environments.”  This seems to ignore the many people (and birds and squirrels and ants) who are good long-term planners.  Giving Lowe the mike, Small continued,“We evolved to strive for resources and seldom, if ever, found ourselves evolutionarily ‘rewarded’ for conscious restraint,” Lowe has written.  Instead, she claims, humans are designed by evolution to work well on the short-term, and forget about the more global view on conserving anything because we just can’t do it.”That seems a pretty broad-brush characterization of the human race.  It also raises the question of how evolution could “design” anything.  Meredith Small failed to distinguish between human design and blind forces of nature, so for the above quotes and the following, she wins a well-deserved SEQOTW prize: There are many forces of evolution, but natural selection, biologists feel, is the most important.  It works like this: All sorts of variation is produced (think SUV, compacts, vans, and sedans) and then the environment (think free market) selects for some and ignores others.  The ignored ones are dropped out of the gene pool (think showroom floor or metal recycling plant), and too bad for them.    In this biological (or economic) system, only the best adapted survive.  So what if evolution is presented with something more sleek, in cool colors, or with tinted windows – if it takes too much energy (gas) to use, it will be selected against.    Natural selection operates on individuals, or individual automobiles companies because not all of them are going bankrupt, and that affects the future of the total gene pool, or automobile business.  That’s how biological life, and capitalist economies, have been shaped over generations.last_img read more

Specialized Molecules Make Cells Work

first_imgWalker with muscle:  A paper by Kaya and Higuchi from the University of Tokyo discussed how myosin motors, the active force-generating machines in muscle, adjust their walking steps with non-linear elasticity.1  Myosins work together in muscle.  Their ability to reduce stiffness and adjust their walk is essential: “the load-dependent changes in the step size are an essential property of skeletal myosin,” the authors said.  Their last sentence explained why this contributes to their effectiveness: “Such molecular properties may be inherent in the assembly of molecular motors and may reduce molecular interference, leading to the high mechanical efficiency of muscle contraction.”  You have your elastic myosins to thank for every simple or complex move you make.  For more stories about myosin this year, see 04/19/2010, 02/19/2010, and 01/19/2010.Junk with control:  It wasn’t long ago when any non-coding region of the genome was considered junk.  No longer; lincRNAs are emerging as stars of regulation and control (see 08/02/2010).  Another finding to that effect was published in Science by an international team from Stanford, Harvard and the Weizmann Institute in Israel.2  They studied one lincRNA called HOTAIR that has two specific binding domains for making histone modifications.  Histone is the protein on which DNA winds.  It contains molecular tags that affect translation – the “histone code” (see 12/22/2009, bullet 5, with its embedded links).    The team found that HOTAIR, an RNA generated from non-coding DNA, is intimately involved with the regulation of histone by forming a scaffold for PRC2 and LSD1 proteins: “The functional consequence of coordinate targeting of PRC2 and LSD1 by HOTAIR is gene repression,” they said.  What they found may apply to other cases: “Some lincRNAs may be ‘tethers’ that recruit several chromatin modifications to their sites of synthesis while other lincRNAs can act on distantly located genes as ‘guides’ to affect their chromatin states,” the concluded.  “On the basis of their dynamic patterns of expression, specific lincRNAs can potentially direct complex patterns of chromatin states at specific genes in a spatially and temporally organized manner during development and disease states.”Repairmen with teamwork:  A team at Zheijiang University in China studied the partners in DNA interstrand cross-link repair, one of many repair pathways active in the genome.  Fanconi anemia is a disease caused by mutations in 13 Fanc genes.3    “Here, we characterize a previously unrecognized nuclease, Fanconi anemia?associated nuclease 1 (FAN1), that promotes ICL repair in a manner strictly dependent on its ability to accumulate at or near sites of DNA damage and that relies on mono-ubiquitylation of the ID complex,” they said, referring to the tagging of a repair site with ubiquitin, a “ubiquitous” cellular tag signaling a site for repair or demolition.  “Thus, the mono-ubiquitylated ID complex recruits the downstream repair protein FAN1 and facilitates the repair of DNA interstrand cross-links.”    For more on DNA repair teams in the cell, see the 07/18/2001, 07/26/2002, 01/30/2003, 02/13/2004, 03/31/2005, 08/14/2007, and 03/14/2010 entries.These three papers are examples of many that are continuously being published in leading journals that (1) explore highly-specific molecules involved in vital cellular processes and (2) say nothing about evolution.  Examples could be easily multiplied.1.  Kaya and Higuchi, “Nonlinear Elasticity and an 8-nm Working Stroke of Single Myosin Molecules in Myofilaments,” Science, 6 August 2010: Vol. 329. no. 5992, pp. 686-689, DOI: 10.1126/science.1191484.2.  Tsai, Manor et al, “Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes,” Science, 6 August 2010: Vol. 329. no. 5992, pp. 689-693, DOI: 10.1126/science.1192002.3.  Liu, Ghosai, Yuan, Chen and Huang, “FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair,” Science, 6 August 2010: Vol. 329. no. 5992, pp. 693-696, DOI: 10.1126/science.1192656.Who needs evolution?  Not these authors.  Not medical science, genetics, or cell biology, either.  Let’s move along, and leave Darwinism to rust in pieces.(Visited 10 times, 1 visits today)FacebookTwitterPinterestSave分享0 Reports continue to show that vital cell processes depend on finely-tuned proteins and RNA molecules.  Most of the papers that discuss these specialized molecules fail to mention how they might have evolved, as shown in three papers in the recent issue of Science.last_img read more

The Books That Taught Me How to Sell

first_imgI had brain surgery 90 days before I went back to working in my family’s business. At the time, I was not allowed to drive, a difficult obstacle to overcome when you have to book sales meetings—or if you need a few things from the grocery store. My younger brother would chauffeur me to appointments until the time I was frustrated by with the realization that my doctors would never release me to drive, even though I only ever had one seizure.While I had always been a reader, during my recovery, I started reading a book a day. I told my neurologist that I was sure my brain was making new neural pathways and that it was on fire. He listened patiently and then told me there was no evidence that my theory was accurate and that it was more likely I was compensating for losing a significant part of my brain. We didn’t yet fully understand neuroplasticity, and it turns out both of us may have been correct.At some point, I started picking up books on sales and business. The first book I stumbled upon was SPIN Selling by Neil Rackham. If you heard my story behind my book, The Lost Art of Closing, it was the three pages where Rackham described “the advance” as a key to success in sales. Once I understood I needed a commitment for another meeting, selling got quite a bit easier. I wrote a list of questions for each part of the SPIN model and started to work towards Implications (clumsily, I might add) and needed payoffs.The book was so helpful that I picked up Major Account Sales Strategy, Rackham’s second book—and in some ways, his better book. I had been winning large accounts in California, but I didn’t have a very strategic view or a process. Mostly I just called on people who spent a lot of money in my category. Major Account Sales Strategy provided me with frameworks for thinking about big deals. I eventually read everything Rackham wrote and multiple times.One book I picked up appeared to be new, but it was quite old at the time I picked it up. The book was Consultative Selling by Mack Hanan. Parts of the book were difficult for me, but what I learned that was useful was Hanan’s idea that you shift the conversation away from price to the increased profit the client will make by adopting your solution. The application of this idea made it easier for me to start sharing the soft costs my clients were not calculating in their overall costs.The Miller Heiman books were both beneficial, The New Strategic Selling and The New Conceptual Sale. The first had me looking at stakeholders differently, even though the evolution of my thought here shows up very differently in Eat Their Lunch, which you might expect since 34 years have passed since they first published Strategic Selling. I don’t remember New Conceptual as well, but I remember it caused me to take sales calls seriously enough to plan them.I read all of Stephen Covey’s work before my brain surgery, and even those books were not on sales, they caused me to recognize I had to improve who I was before I could improve my sales results. They also led me to read a lot more books on business improvement.Some books that were not sales-related on their face were valuable to me. One of those books was Tom Peter’s Circle of Innovation, a book that made me think deeply about differentiation and allowed me to put technological solutions long before my larger competitors could do so, grabbing a competitive advantage in big deals. Another was Michael Hammer’s The Agenda: What Every Business Must Do to Dominate the Decade. From this work, I took the idea that my business existed to take care of its customers. I started to present how what I did for my clients helped them serve their customers. Pondering that idea for a while is an excellent way to get better at selling.One of the more useful and transformative books I read was Let’s Get Real or Let’s Not Play by Mahan Khalsa. The ideas and the dialogue in this book massively improved my ability to have conversations about the changes the customer would have to make to produce the results they needed.There were hundreds of other books on sales and business I read, all of which had some value, even if I didn’t recognize it right away. These few were core to my development and the ones I remember as changing my sales results.last_img read more

Eduard Folayang, Shinya Aoki meet again in stacked ONE Championship card in Japan

first_imgIs Luis Manzano planning to propose to Jessy Mendiola? Private companies step in to help SEA Games hosting Alvarez will face top lightweight contender Timofey Nastyukhin of Russia while Johnson, widely considered one of the best pound-for-pound fighters in history, will take on hometown bet Yuya Wakamatsu in the card.In the other blockbuster title bouts, Xiong Jing Nan faces challenger Angela Lee, who is looking for to become ONE’s first two-division champion, in the ONE women’s strawweight bout while Myanmar hero Aung La N Sang defends his middleweight strap against Ken Hasegawa out of JapanThe ONE Flyweight World Grand Prix will also kick off at ONE: A New Era with initial bouts yet to be announced.ADVERTISEMENT SEA Games: Biñan football stadium stands out in preparedness, completion LATEST STORIES Don’t miss out on the latest news and information. ONE Championship is pulling out all the stops for its debut card in Japan.ADVERTISEMENT SEA Games: Biñan football stadium stands out in preparedness, completion TS Kammuri to enter PAR possibly a day after SEA Games opening Hotshots rulecenter_img PH underwater hockey team aims to make waves in SEA Games PLAY LIST 02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games02:11Trump awards medals to Jon Voight, Alison Krauss Sports Related Videospowered by AdSparcRead Next Lacson: 2019 budget delay due to P75-B House ‘insertion’ The premier mixed martial arts organization have put together a slambang ONE: A New Era fight night on March 31 that will see three world title defenses and the first appearance of ONE Championship’s two prized recruits.Team Lakay bet Eduard Folayang is set to defend his ONE lightweight world title against the same person he stopped to get the crown in 2016.FEATURED STORIESSPORTSPrivate companies step in to help SEA Games hostingSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionSPORTSUrgent reply from Philippine ‍football chiefFolayang will face Japanese icon Shinya Aoki in a long-awaited rematch for the belt four months after the Bagui0-native recaptured the lightweight throne with a unanimous decision win over Amir Khan.Demetrious Johnson and Eddie Alvarez, the promotion’s biggest signings last year, are also scheduled to make their much-awaited debut in the ONE Championship cage. Hotel management clarifies SEAG footballers’ kikiam breakfast issue LOOK: Joyce Pring goes public with engagement to Juancho Triviño MOST READ View commentslast_img read more

Kaya’s Bedic tortures former team; Ceres routs Air Force

first_imgLATEST STORIES Ceres’ win came a day after midfielder Kevin Ingreso announced he was immediately leaving the club after three seasons. Sources said the Filipino international is set to sign with Thai league powerhouse Buriram United.Sports Related Videospowered by AdSparcRead Next Jovin Bedic tormented his former team as Kaya-Iloilo overcame a gutsy challenge from Stallion Laguna, 2-0, while Ceres Negros nailed a breakthrough win on Wednesday in the Philippines Football League.Facing the club he played with for three seasons until 2016, Bedic converted a 28th minute penalty at Biñan Football Stadium before Jordan Mintah sealed maximum points with a second half strike for his fourth goal in two matches as Kaya maintained its two point lead at the top.ADVERTISEMENT Catholic schools seek legislated pay hike, too Ramirez relents, accepts CDM post Private companies step in to help SEA Games hosting Ethel Booba twits Mocha over 2 toilets in one cubicle at SEA Games venue Two-day strike in Bicol fails to cripple transport DA eyes importing ‘galunggong’ anew ‘Rebel attack’ no cause for concern-PNP, AFP “We needed to be 100 percent focused to get the three points,” Kaya coach Noel Marcaida said. “Stallion will always be tough to beat. But the players did just enough to take the win. It’s an important win because we know Stallion is one of the contenders for the title this season.”Over at Rizal Memorial Stadium, defending champion Ceres Negros gave Philippine Air Force a rude welcome to the league with a 5-0 thumping thanks to a hattrick from Bienve Marañon.FEATURED STORIESSPORTSPrivate companies step in to help SEA Games hostingSPORTSPalace wants Cayetano’s PHISGOC Foundation probed over corruption chargesSPORTSSingapore latest to raise issue on SEA Games food, logisticsMarañon scored his first goal via a free kick in the first half as the Airmen put plenty of players behind the ball to limit the Ceres attack.But the floodgates opened in the second half as Curt Dizon grabbed the second goal, before Marañon added two more later. MOST READ PH billiards team upbeat about gold medal chances in SEA Games PLAY LIST 03:07PH billiards team upbeat about gold medal chances in SEA Games00:50Trending Articles02:25PH women’s volleyball team motivated to deliver in front of hometown crowd02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games02:11Trump awards medals to Jon Voight, Alison Krauss Cayetano: Senate, Drilon to be blamed for SEA Games mess PDEA chief backs Robredo in revealing ‘discoveries’ on drug war View comments Don’t miss out on the latest news and information. last_img read more