Category : juctaqohzhtz

Brazilian businesswoman, miner arraigned with human trafficking

first_imgChief Magistrate Ann McLennan on Friday remanded a Brazilian national along with a miner after they were slapped with separate charges of human trafficking when they appeared at the Georgetown Magistrates’ Courts.Thirty-two-year-old Christina Rodriquez Gomes and 50-year-old Arnold Melville of Iteringbang, Cuyuni River, Region Seven (Cuyuni-Mazaruni) were not required to plea to the indictable charge.The indictable charge against Gomes alleged that between November 4 and 28, 2018, at her business place, the Ola Hotel, she engaged in Trafficking In Persons (TIP) by harbouring two Venezuelan women by abusing their positing for the purpose of labour exploitation.Another charge read that on the same dates and location, Gomes confiscated their travel documents.The accused was represented by Attorney Siand Dhurjon, who in a bail application, informed the court that his client received application from the Venezuelan women to be hired as cooks but they were hired as maids instead and were paid on a weekly basis.He further stated that this issue stemmed from a misunderstanding between the women and their employer. However, she was remanded to prison until January 3, 2019.On the other hand, Melville was slapped which charges alleging that between November 4 and 28, 2018, at Iteringbang, he assisted Gomes by recruiting and transporting the two women by means of deception for the purpose of labour exploitation. He was represented by Attorney Clyde Forde who made an unsuccessful bail application. He too was remanded to prison until March 19, 2018.His matter was transferred to the Kamarang Magistrate’s Court.last_img read more

BC Children in Need

first_imgThe N-D-P says the provincial government is dragging its heels, in implementing recommendations, to improve care for special needs children, in government care.Opposition leader Carole James has pointed to a report by the provincial children’s watchdog, on recommendations she made for improvements last February.The NDP leader notes the watchdog found no progress on wait lists and monitoring outcomes and, limited progress on serving aboriginal children and families.However, Children’s Minister Tom Christensen says, the government has tripled funding for special needs children since 2001.But that note he also sayd, he takes the new report seriously and, is working to improve the special needs services. – Advertisement –last_img read more

Debris from high winds wreaks havoc on residents, property

first_imgThe cold front, which swept down from the north but brought little moisture, helped push some of those high winds down toward the surface, Kittell added. In Los Angeles, the number of Department of Water and Power customers without power jumped to nearly 100,000 customers, at one point increasing by 40,000 in less than two hours, said the utility’s Gale Harris. Hardest hit were Woodland Hills, Van Nuys, Winnetka, North Hollywood, Eagle Rock, Highland Park, Sylmar, Toluca Lake, Silver Lake, Atwater and the Los Feliz areas of Los Angeles, Harris said. Gusting winds were howling across many parts of the Southland, uprooting large trees in Toluca Lake and Sherman Oaks. The National Weather Service issued wind advisories in the San Fernando, San Gabriel and Santa Clarita valleys, and issued high wind warnings in the Antelope Valley and Los Angeles County mountains. The Weather Service reported peak winds Thursday of 45 mph in Van Nuys, 48 mph in Burbank, 35 mph in downtown Los Angeles and 54 mph in Lancaster. Correspondent Brian Day contributed to this City News Service story.160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set! In La Mirada, a tree was blown over into the street on Weeks Drive at La Mirada Boulevard, which caused no damage or injuries, and was quickly cleaned up, said Norwalk sheriff’s Lt. Myron Johnson. In La Puente, the winds knocked a basketball hoop onto a 52-year-old woman about 1 p.m., said Lt. Jaime Baltazar of the sheriff’s Industry station. There was no report on her condition. Baltazar also said a fallen electrical wire started a small backyard grass fire on Eseverri Lane in La Habra Heights. The passing of a cold front overnight Wednesday combined with a southern shift of the jet stream to cause the high winds, said metereologist Ryan Kittell of the National Weather Service. “One of the main reasons was the jet stream right over us, which only happens a few times a year,” said Kittell of the high-altitude winds, which typically travel at speeds upwards of 130 mph at 30,000 feet. WHITTIER – High winds knocked out electricity Thursday to more than 110,000 Los Angeles Department of Water and Power and Southern California Edison customers, authorities said. As of 7 p.m., about 2,200 Edison customers in the San Gabriel Valley remained without power, said Edison spokesman Steven Conroy. Montebello customers had the longest waits to get their power back on, said Conroy, though Sierra Madre, San Gabriel, Arcadia, Alhambra, and Monrovia also had power outages lingering into the night. A tree in a residential neighborhood was blown over and fell onto a car about 3 p.m. on El Braso Drive near Messina Drive in Whittier, said Whittier police Sgt. Carlos Solorza, but no other damage or wind related problems were reported. last_img read more

GIRLS VOLLEYBALL ROUNDUP North Torrance overpowers El Segundo

first_img AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREGame Center: Chargers at Kansas City Chiefs, Sunday, 10 a.m.Also in the Pioneer League … Torrance 3, Lawndale 0: Chelsea Tupuola had 11 kills for Torrance in a 25-14, 25-5, 26-24 win at Lawndale (1-7 in league). Ashley Parker had three aces and served for seven straight points in the second game for Torrance (13-7, 5-3). South Torrance 3, Centennial 0: Danielle Lindahl had six kills, Sarah Wachtfogel had nine assists and Katie Kuehn had 11 aces to lead South (22-8, 7-1) to a 25-4, 25-8, 25-3 victory at Centennial (0-8). In the Bay League … Palos Verdes 3, West Torrance 2: Shauna Moss had 12 kills and 11 digs in a 25-16, 25-12, 20-25, 17-25, 15-11 win for host Palos Verdes (12-8, 4-4). Stacie Groat added nine blocks and Caroline Daly had eight. Katie Colin had 36 assists and 17 digs for West Torrance (8-12, 1-7). Laura Day added 14 kills and seven digs for West. In the Camino Real League … Serra 3, St. Monica 1: Seini Tukutau had 20 kills, five digs and four aces in a 25-11, 20-25, 25-12, 25-21 win for visiting Serra (10-6, 3-4). Marielle Brosmer recorded nine kills, 16 digs and four aces. Christine Barba added 34 assists for Serra. Mary Star 3, Cantwell 1: Robin Skale had nine kills and four aces to lead host Mary Star in a 25-4, 20-25, 25-14, 25-21 win. Lauren Costa had 26 assists and three aces. In the Del Rey League … Bishop Montgomery 3, St. Bernard 0: Jennifer Edmond had eight kills and Sarah Prather had five kills to lead host Bishop Montgomery (20-6, 7-0) to a 25-13, 25-9, 25-15 Del Rey League title-clinching victory. Ashley Thompson had eight kills for St. Bernard (8-12, 0-6). In the Marine League … Carson 3, King-Drew 0: Kristiana Tuaniga had 15 kills and 10 digs to lead visiting Carson (12-2, 10-2) in a 25-15, 25-19, 25-14 win. Rosita Fualau added nine kills and six digs. Abigail Villena recorded 25 assists, eight digs and three kills. San Pedro 3, Washington 0: Shannon Miller had 12 kills and three aces in a 25-7, 25-6, 25-13 for visiting San Pedro (12-1, 12-0). Alexis Hathaway added nine kills. Marissa Bubica added 10 aces and 16 assists. Narbonne 3, Banning 0: Jessica Kerr had seven kills and Shainiece Gonsalvez had four digs and six assists to lead Narbonne (8-5, 8-4) to a 25-23, 25-20, 25-13 victory at Banning.160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set! From staff reports Ilyanna Hernandez had 20 kills and eight aces to help North Torrance move a step closer to its fourth straight Pioneer League title in a 25-14, 22-25, 25-15, 25-18 win at El Segundo. Kristen McNeese had all 14 of her kills in the final three games, including seven in the deciding game to clinch the victory for North (19-3, 8-0). The win marked the first time in four seasons that North has swept the season series with El Segundo, with whom it shared the league crown in 2004 and 2005. Jen Stutzel led El Segundo (4-10, 3-5) with 11 kills. last_img read more

Ty Treadway puts on best game face
first_imgAlex Trebek, Pat Sajak and Ty Treadway? They are the hosts of the three game shows created by the late Merv Griffin currently on the air. While Trebek of “Jeopardy” and Sajak of “Wheel of Fortune” are game show institutions, Treadway is the new kid on the block as the host of “Merv Griffin’s Crosswords.” “It’s an amazing and surreal experience,” Ty told me recently. “I hope I can live up to what they’ve done. The beauty of both of them is they make it look so easy when I know it’s not.” Just four months before he died, Griffin personally chose the 40-year-old Treadway for the gig and his selection was definitely a decision to appeal to younger viewers. AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREStriving toward a more perfect me: Doug McIntyre “Actually I’m 85,” Ty joked. “I just look younger. It’s all the Botox.” He’s still amazed at how quickly he landed a job that he felt was a real long shot. “I thought I was going to have to go through 20 or 30 levels of executives before I ever got a glimpse of the man behind the curtain himself. As fate would have it, I walked into that very first meeting on March 2 and the first hand that reached out to shake mine was Merv himself. … I couldn’t feel any more honored or privileged to hopefully carry the torch for his legacy.” Ty gained fame on the ABC soap “One Life to Live” in 2000, and after his character was killed off a year later he returned as his nicer twin brother. He spent three more years on the show until his character went insane. The soap exposure led to his co-hosting “Soap Talk” on the Soapnet cable network with Lisa Rinna. They had a four-year run and were nominated for Emmys three of those years. Ty has clearly learned the ropes of being a good host. But c’mon, doesn’t he ever miss being a soap stud? “What do you mean? I’m still a soap stud! (laughs). There are things that you miss about it; there are things that you don’t miss. You don’t miss having to take your shirt off every five seconds and I’m really glad I have a job that lets me use my other assets, such as my brain. But occasionally I think, well, maybe I’ll take my shirt off for `Crosswords.’ No, I’m kidding. You get to eat a little bit, you get to enjoy life a little bit more. You don’t always have to be on your toes workout-wise.” And hosting means it’s no longer all about him. “Hosting, a lot of it is about the other person,” Ty said. “Their No. 1 job is to make people feel comfortable and bring out the best in them while entertaining people in the downtime in between.” Looks like he’s got the job down.160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set!last_img
RAPHOE’S CATHERINE IS CHOSEN AS DONEGAL ROSE

first_imgA young woman from Raphoe has been chosen as the Donegal Rose to go forward for the Rose of Tralee contest.Catherine McCarron was a popular choice at a gala function to choose Donegal’s rose at Harvey’s Point Hotel last night.TV3 personality Noel Cunningham interviewed the ladies and each performed a chosen piece. Catherine was eventually chosen as the popular winner from the ten finalists. RAPHOE’S CATHERINE IS CHOSEN AS DONEGAL ROSE was last modified: March 31st, 2013 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:Catherine McCarronRose of Traleelast_img read more

Europa League: Arsenal hoping to seal spot in last 32 as United are away to Astana

first_img Tags: arsenalAstanaEintracht Frankfurteuropa leagueman United Arsenal will reach the last 32 if they avoid defeat on Thursday. (PHOTO/Courtesy)Astana vs Man UnitedAstana Arena, AstanaThursday, 28-11-2019 @6:50pmRef: Donatas Rumsas (Lit)Manchester United manager Ole Gunnar Solskjaer confirmed several academy players will take part in the game against Astana. He has included just four senior players – Lee Grant, Axel Tuanzebe, Luke Shaw and Jesse Lingard. Solskjaer has also suggested 19-year-old defender Max Taylor will make his debut.For Astana, only striker Firmin Mubele is unavailable due to a knee injury sustained at the back end of September.Manchester United’s 1-0 win against Astana on MD1 was the first-ever meeting between an English side and a Kazakh side in all European competition. United are yet to concede a goal in the Europa League this season – no side has ever kept a clean sheet in each of their opening five group stage games in a campaign in the competition. Astana have lost their last six Europa League games by an aggregate score of 1-17. Only Dudelange (15) have conceded more goals in this season’s competition than Astana (14). Manchester United have managed just one shot on target across their two away games in the Europa League this season, with that effort coming from the penalty spot against FK Partizan. 18-year-old Mason Greenwood has been involved in 60 percent of Manchester United’s five goals in the Europa League this season (two goals, one assist).Arsenal vs Eintracht FrankfurtEmirates Stadium, LondonThursday, 28-11-2019 @11pmRef: Ruddy BuquetUnder-pressure boss Unai Emery is likely to give some of the younger members of his first-team squad game time and possibly hand a return to Granit Xhaka, who hasn’t featured since he was booed off against Crystal Palace. Dani Ceballos is out with hamstring trouble while Hector Bellerin and Sead Kolasinac are being assessed ahead of the game.Frankfurt are without two long-term absentees in defender Marco Russ and goalkeeper Kevin Trapp. Aside from the pair, they have a fully-fit squad to choose from.Arsenal won the reverse fixture against Eintracht Frankfurt 3-0 on MD1, in what was the first-ever meeting between the sides. Eintracht Frankfurt have won just one of their six away games against English opponents, with that victory coming back in 1967 against Burnley in the Fairs Cup (2-1). Arsenal have lost more European home games against German sides than they have against opponents from any other nation (6). If Arsenal avoid defeat, it would see them progress past the first group stages of a Champions League/Europa League campaign for the 20th consecutive season, with the Gunners last failing to do so in the 1999-00 Champions League. Eintracht Frankfurt have lost two of their four Europa League games this season (W2), more than they had in their previous 18 in the competition (W11 D6 L1).The other games to be played Thursday, 28-11-2019 @6:50pm-Krasnodar vs Basel-Trabzonspor vs GetafeThursday, 28-11-2019 @8:55pm-Young Boys vs Porto-Feyenoord vs Rangers-Saint Etienne vs Gent-Oleksandria vs Wolfsburg-Ferencvaros vs Espanyol-CSKA Moscow vs Ludogorets-Istanbul BB vs Roma-Wolfsburger vs Gladbach-Besiktas vs Slovan Bratislava-Braga vs Wolves-AZ vs PartizanThursday, 28-11-2019 @11pm-Lazio vs CFR Cluj-Celtic vs Rennes-Vitoria Guimaraes vs Standard Liege-Sevilla vs Qarabag-Dudelange vs APOEL-Malmo vs Dynamo Kiev-Lugano vs Copenhagen-Sporting Lisbon vs PSG-Rosenberg vs LASKComments last_img read more

Lampard ‘to be offered £1m a month to leave Chelsea’

first_imgFrank Lampard will be offered £1m a month after tax to leave Chelsea and move to China, according to The Sun.It is claimed Lampard is wanted by former Blues team-mate Didier Drogba’s club Shanghai Shenhua, as well as their Chinese Super League rivals Beijing Guoan.The midfielder’s contract expires next summer, meaning he will be free to talk to other clubs in January unless he agrees a new deal at Stamford Bridge.Lampard has repeatedly stated that he is keen to stay at Chelsea, while manager Roberto Di Matteo has said that he expects him to be offered a new contract.The Sun also say QPR chiefs will decide this week whether to replace manager Mark Hughes with Harry Redknapp.It is suggested that the club could opt to make the change during the international break.The Daily Express say Hughes has been given two months to turn things around or he will be sacked.It is claimed that there is major disquiet among senior club officials at Loftus Road, some of whom supposedly want Hughes out now.Chairman Tony Fernandes has pledged his support for the Welshman but is said to be planning to wield the axe if results have not improved by December.This page is regularly updated.Follow West London Sport on TwitterFind us on Facebooklast_img read more

Evolution As Catch-All Explanation

first_imgIn the scientific institutions and the media, Evolution is the default explanation for everything in nature (and as Small opined, even for human manufacturing and economics).  Most of the time Evolution doesn’t require justification or evidence.  It is applied in broad, sweeping generalities from the authorities.  The explanations are pronounced dogmatically as if to be accepted on faith by the common people.  In a sense, then, Evolution (with a capital E) plays the same role as gods and goddesses in ancient cultures.Silly, silly, silly.  These people only get away with saying such things because we are not laughing loud enough.  Look at them.  They worship cartoony idols (King Charles, Popeye, Yoda and Tinker Bell) that have magical powers.  They say things that not only make no sense, they plagiarize design words and contradict their own core beliefs.  They justify humans’ worst character flaws as artifacts of an animal past.  Get out on the yellow brick road and sing We’re off the shame the Wizard, the blunderful Wizard of Flaws (see lyrics in the 09/05/2008 commentary) as you accomplish your mission to expose charlatanry and bring science back to the real world.(Visited 36 times, 1 visits today)FacebookTwitterPinterestSave分享0 If you were taught a precise definition of neo-Darwinism in school, it doesn’t seem to matter to many evolutionists in the media.  In practice, the word “Evolution” seems to act as a catch-all category for explaining anything and everything – whether or not random mutation and natural selection were involved.  Some purpose and design can even be tossed into the mix as long as Evolution is the hero of the story.  Here are some recent examples of how Evolution is employed to explain whatever:Evolution the tool user:  “Evolution has a ‘toolkit’ and when it needs to do a particular job, such as see light, it uses the same toolkit again and again.”  These are the words of Margaret McFall-Ngai [U of Wisconsin-Madison] in Science Daily, explaining why squid can sense light through their light-emitting organs.  The article explained that “molecular machinery” is involved – tangible evidence not of design, but that Evolution has been at work with its toolkit.Guppy race:  Evolution is slow and gradual – except when it is fast and furious.  “What’s the secret to surviving during times of environmental change?” asked Science Daily.  “Evolve…quickly.”  (This sounds like a version of the bumper sticker, “Evolve or perish.”)  Guppies in Trinidad have apparently altered their reproductive habits in just eight years when transplanted to different streams – one with more predators, one with fewer.  How this constitutes evolution when the reproductive apparatus was the same before and after was not explained, but “fitness differences” were defined in terms of survival rate (see 10/30/2002, “Fitness for Dummies”).  Surprisingly, after 150 years of Darwinism, “This is one of only a few studies to look at adaptation and survival in a wild population,” the article said.Spanish hominid:  Evolution got the credit for a fossil monkey with “modern New Scientist) – something that might make Europeans feel superior once again as being in the forefront of human evolution.Mosquitos vs. turtles:  Who will win the evolutionary arms race in the Galapagos?  The mosquitos or the giant tortoises?  Science Daily seems alarmed about the danger to the long-time residents that are so popular with tourists: “Mosquito Evolution Spells Trouble For Galapagos Wildlife,” the article announced.  It said that an “ancient” mosquito population came to the islands 200,000 years ago and has recently developed a taste for tortoise blood.  Park officials are very concerned that diseases that could be introduced by tourists could spread to the island inhabitants, so they are taking precautions by spraying the interiors of planes arriving on the islands.  “It is absolutely vital that these control measures are maintained and carried out rigorously, otherwise the consequences could be very serious indeed,” a scientist said.  He did not explain why there should be a cause for concern, since all of the inhabitants of the islands supposedly evolved according to a well-known evolutionary dogma: the founder principle (see 05/08/2002 and 02/10/2009, bullet 4).  Are they ranking the organisms according to some arbitrary rule?  Are they claiming that human beings have some special stewardship responsibility over the animal kingdom?Saved by the junk:  Functional “junk DNA” has been an argument against evolution, but they have found a way to turn it into an argument for evolution.  PhysOrg printed a story that now claims junk DNA is vital to an animal’s survival – and therefore its evolution – because it allows an organism to adapt quickly.  Tandem repeats (once a category of junk DNA) have been found to influence the activity of neighboring genes.  This means they “may allow organisms to tune the activity of genes to match changing environments – a vital principle for survival in the endless evolutionary race.”  Researchers explained, “If this was the real world, only cells with the repeats would be able to swiftly adapt to changes, thereby beating their repeat-less counterparts in the game of evolution.  Their junk DNA saved their lives.”  They did not say who is playing the game or who wrote the game in the first place.Animorals:  Animals can tell right from wrong, claimed The Telegraph.  “Until recently, humans were thought to be the only species to experience complex emotions and have a sense of morality,” the article by Richard Gray said.  “But Prof Marc Bekoff, an ecologist at University of Colorado, Boulder, believes that morals are ‘hard-wired’ into the brains of all mammals and provide the ‘social glue’ that allow often aggressive and competitive animals to live together in groups.”  Gray did not explain what the moral standard was by which to judge moral behavior, nor why social glue is a good thing.  Some aggressive and competitive animals are loners.  If morality is hard-wired, is it really morality?  Who is the judge?Say what?  One article on Science Daily claim that a genetic change to the language-related FOXP2 gene in mice to make them mimic the human form of the gene speaks “volumes about our evolutionary past” (Note: the mice do not talk; they just squeak a little differently.)  Presumably, “Those differences offer a window into the evolution of speech and language capacity in the human brain.”  The scientists involved admitted that “Currently, one can only speculate about the role these effects may have played during human evolution.”  But then, another Science Daily four days earlier had announced, “More Genetic Differences Between Mice And Humans Than Previously Thought.”  It further claimed that some of the newly-analyzed mouse genes are “evolving at an unusually rapid pace, probably as a result of an evolutionary ‘arms race’ among mice and their reproductive cells.”Small talk on cars:  Evolution even applies to car companies.  That’s the point Meredith Small tried to make on Live Science.  Her article, “How Evolution Could Sink (or Save) GM,” contained the following statement, reminiscent of Rockefeller-era social Darwinism: “It would seem that the country should act as a collative [sic; collective?] and care about this,” (i.e., the bankruptcy of General Motors).  “But the reality is that capitalism is like evolution by natural selection, and natural selection can be a harsh reality.”  Taking the edge off, she launched into a discussion about group selection as a possible offset to the ruthlessness of natural selection.  But group selection, she said, doesn’t seem to make a lot of sense.  Why should we care about the job losses of people we don’t even know?  She quoted Bobbi Lowe (U of Michigan) who believes “humans are not well designed to operate” by caring for distant members of our species.  We only care about close kin, because that was “critical in our ancestral past when humans lived in small groups,” she explained.  “We also don’t plan well for the future because our hominid history was marked by uncontrollable, unpredictable environments.”  This seems to ignore the many people (and birds and squirrels and ants) who are good long-term planners.  Giving Lowe the mike, Small continued,“We evolved to strive for resources and seldom, if ever, found ourselves evolutionarily ‘rewarded’ for conscious restraint,” Lowe has written.  Instead, she claims, humans are designed by evolution to work well on the short-term, and forget about the more global view on conserving anything because we just can’t do it.”That seems a pretty broad-brush characterization of the human race.  It also raises the question of how evolution could “design” anything.  Meredith Small failed to distinguish between human design and blind forces of nature, so for the above quotes and the following, she wins a well-deserved SEQOTW prize: There are many forces of evolution, but natural selection, biologists feel, is the most important.  It works like this: All sorts of variation is produced (think SUV, compacts, vans, and sedans) and then the environment (think free market) selects for some and ignores others.  The ignored ones are dropped out of the gene pool (think showroom floor or metal recycling plant), and too bad for them.    In this biological (or economic) system, only the best adapted survive.  So what if evolution is presented with something more sleek, in cool colors, or with tinted windows – if it takes too much energy (gas) to use, it will be selected against.    Natural selection operates on individuals, or individual automobiles companies because not all of them are going bankrupt, and that affects the future of the total gene pool, or automobile business.  That’s how biological life, and capitalist economies, have been shaped over generations.last_img read more

Specialized Molecules Make Cells Work

first_imgWalker with muscle:  A paper by Kaya and Higuchi from the University of Tokyo discussed how myosin motors, the active force-generating machines in muscle, adjust their walking steps with non-linear elasticity.1  Myosins work together in muscle.  Their ability to reduce stiffness and adjust their walk is essential: “the load-dependent changes in the step size are an essential property of skeletal myosin,” the authors said.  Their last sentence explained why this contributes to their effectiveness: “Such molecular properties may be inherent in the assembly of molecular motors and may reduce molecular interference, leading to the high mechanical efficiency of muscle contraction.”  You have your elastic myosins to thank for every simple or complex move you make.  For more stories about myosin this year, see 04/19/2010, 02/19/2010, and 01/19/2010.Junk with control:  It wasn’t long ago when any non-coding region of the genome was considered junk.  No longer; lincRNAs are emerging as stars of regulation and control (see 08/02/2010).  Another finding to that effect was published in Science by an international team from Stanford, Harvard and the Weizmann Institute in Israel.2  They studied one lincRNA called HOTAIR that has two specific binding domains for making histone modifications.  Histone is the protein on which DNA winds.  It contains molecular tags that affect translation – the “histone code” (see 12/22/2009, bullet 5, with its embedded links).    The team found that HOTAIR, an RNA generated from non-coding DNA, is intimately involved with the regulation of histone by forming a scaffold for PRC2 and LSD1 proteins: “The functional consequence of coordinate targeting of PRC2 and LSD1 by HOTAIR is gene repression,” they said.  What they found may apply to other cases: “Some lincRNAs may be ‘tethers’ that recruit several chromatin modifications to their sites of synthesis while other lincRNAs can act on distantly located genes as ‘guides’ to affect their chromatin states,” the concluded.  “On the basis of their dynamic patterns of expression, specific lincRNAs can potentially direct complex patterns of chromatin states at specific genes in a spatially and temporally organized manner during development and disease states.”Repairmen with teamwork:  A team at Zheijiang University in China studied the partners in DNA interstrand cross-link repair, one of many repair pathways active in the genome.  Fanconi anemia is a disease caused by mutations in 13 Fanc genes.3    “Here, we characterize a previously unrecognized nuclease, Fanconi anemia?associated nuclease 1 (FAN1), that promotes ICL repair in a manner strictly dependent on its ability to accumulate at or near sites of DNA damage and that relies on mono-ubiquitylation of the ID complex,” they said, referring to the tagging of a repair site with ubiquitin, a “ubiquitous” cellular tag signaling a site for repair or demolition.  “Thus, the mono-ubiquitylated ID complex recruits the downstream repair protein FAN1 and facilitates the repair of DNA interstrand cross-links.”    For more on DNA repair teams in the cell, see the 07/18/2001, 07/26/2002, 01/30/2003, 02/13/2004, 03/31/2005, 08/14/2007, and 03/14/2010 entries.These three papers are examples of many that are continuously being published in leading journals that (1) explore highly-specific molecules involved in vital cellular processes and (2) say nothing about evolution.  Examples could be easily multiplied.1.  Kaya and Higuchi, “Nonlinear Elasticity and an 8-nm Working Stroke of Single Myosin Molecules in Myofilaments,” Science, 6 August 2010: Vol. 329. no. 5992, pp. 686-689, DOI: 10.1126/science.1191484.2.  Tsai, Manor et al, “Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes,” Science, 6 August 2010: Vol. 329. no. 5992, pp. 689-693, DOI: 10.1126/science.1192002.3.  Liu, Ghosai, Yuan, Chen and Huang, “FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair,” Science, 6 August 2010: Vol. 329. no. 5992, pp. 693-696, DOI: 10.1126/science.1192656.Who needs evolution?  Not these authors.  Not medical science, genetics, or cell biology, either.  Let’s move along, and leave Darwinism to rust in pieces.(Visited 10 times, 1 visits today)FacebookTwitterPinterestSave分享0 Reports continue to show that vital cell processes depend on finely-tuned proteins and RNA molecules.  Most of the papers that discuss these specialized molecules fail to mention how they might have evolved, as shown in three papers in the recent issue of Science.last_img read more